Cardiac glycoside receptors and positive inotropy. Evidence for more than one receptor?

نویسنده

  • E Erdmann
چکیده

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منابع مشابه

Cardiac Glycoside Receptors and Positive Inotropy

With Contributions by L .Brown, W.H.Barry , D.Charlemagne, E. Erdmann, A . A . L.Fox, U.Fricke, W.H.van Gilst, T.Godfraind, K.Greeff, M.Heller , Κ.-Ο. Haustein, G. Isenberg, R.Jacob, T.Kazazoglou, D . K i m , K.Kochsiek, J .M.Koomen, W.Krawietz, M.Lazdunski, L.G.Lelievre, H.Lül lmann, P.Mansicr, E.Noack, D.Noble, D.Palm, Th.Peters, H.-H.Pri l lwitz , J.F.Renaud, B.Rossi, J . A . M . Schevers, T...

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Glycoside inotropy in the absence of an increase in potassium efflux in the rabbit heart.

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Nuclear Compartmentalization of α1-Adrenergic Receptor Signaling in Adult Cardiac Myocytes

Although convention dictates that G protein-coupled receptors localize to and signal at the plasma membrane, accumulating evidence suggests that G protein-coupled receptors localize to and signal at intracellular membranes, most notably the nucleus. In fact, there is now significant evidence indicating that endogenous alpha-1 adrenergic receptors (α1-ARs) localize to and signal at the nuclei in...

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Rat cardiac ventricle has two Na+,K+-ATPases with different affinities for ouabain: developmental changes in immunologically different catalytic subunits.

The mechanism of the inotropic effect of cardiac glycosides on the heart has long been controversial. Inotropic effects at low concentrations of cardiac glycosides indicate more than one class of receptor or more than one cellular mechanism. In the brain of the rat, high- and low-affinity cardiac glycoside receptors have been shown to be associated with two structurally different isoforms of th...

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Reversal of Ouabain and Acetyl Strophanthidin

sponse to additionally added digitalis, and relation of antibody effects on digitalis-induced automaticity and contracture to reversal of inotropy. Specific antibody (but not control antibody) in 1.1-1.5-fold molar excess over cardioactive steroid concentrations blocked positive inotropic effects of ouabain and acetyl strophanthidin, and gradually reversed established contractile effects of the...

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عنوان ژورنال:
  • Basic research in cardiology

دوره 79 Suppl  شماره 

صفحات  -

تاریخ انتشار 1984